EDUCATION
STANFORD UNIVERSITY
Stanford School of Medicine
Stanford, CA
Doctor of Medicine
RICE UNIVERSITY
Houston, TX
Graduated - B.A., Honors in Cognitive Sciences with specialization in Neuroscience, 2018.
Awards:
- Distinction in Research and Creative Works (Evolutionary Biology and Ecology) - 2018
- Student Speaker at American Physician Scientists Association Southern Annual Meeting - 2018
- Plenary Speaker at Stanford Research Conference - 2018
- Omega Psi Cognitive Sciences Honor Society - 2018
- President’s Honor Roll - 2016, 2017, 2018
- Head Fellow - 2018
- Academic Fellow (Lovett College) - 2017, 2018
RESEARCH
SARDIELLO LABORATORY
Jan and Dan Duncan Neurological Research Institute
Baylor College of Medicine (Department of Molecular and Human Genetics) and Texas Children's Hospital
Undergraduate Researcher: 2015-2020
- Aminode: Project lead for novel research on computational amino acid analysis and human proteomics, for the identification of evolutionary constrained regions.
- Neuronal ceroid lipofuscinosis types 6 and 8: designed, assisted, and performed experiments to elucidate the roles of disease-linked genes CLN6 and CLN8.
- Project lead on novel research for Atypical TPP1 Deficiency (SCAR7)
Peer-reviewed Publications:
- Chang, K.T., Guo, J., di Ronza, A. and Sardiello, M., 2018. Aminode: identification of evolutionary constraints in the human proteome. Scientific reports, 8(1), pp.1-8.
- di Ronza, A., Bajaj, L., Sharma, J., Sanagasetti, D., Lotfi, P., Adamski, C.J., Collette, J., Palmieri, M., Amawi, A., Popp, L., Chang, K.T., Meschini, M.C., Leung, H.E., Segatori, L., Simonati, A., Sifers, R.N., Santorelli, F.M., and Sardiello, M. 2018. CLN8 is an endoplasmic reticulum cargo receptor that regulates lysosome biogenesis. Nature cell biology, 20(12), pp.1370-1377.
- Bajaj L, Sharma J, di Ronza A, Zhang P, Eblimit A, Pal R, Roman D, Collette JR, Booth C, Chang KT, Sifers RN, Jung SY, Weimer JM, Chen R, Schekman RW, Sardiello M., 2020. A CLN6-CLN8 complex recruits lysosomal enzymes at the ER for Golgi transfer. Journal of Clinical Investigation, 130(8), pp.4118-4132.
NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (NASA)
Human Systems Integration Division, Johnson Space Center
Human Factors Engineer: 2017-2018
- Designed and performed experiment evaluating electroencephalography (EEG) devices and human interface devices for the Orion Multi-Purpose Crew Vehicle (MPCV).
- Collected EEG data on human participants during flight simulations to analyze changes in individual and team alertness, workload, and other cognitive functions.
- Evaluated EEG hardware as cognitive monitoring equipment for the Orion spacecraft program.
CONTACT
Kevin T. Chang
Stanford University
kevinchang4101 (at) gmail.com